weed
"There are numerous active ingredients in marijuana, the primary being the psychoactive molecules tetrahydrocannabinol (THC) and cannabidiol (CBD), which have not well-understood cascading physiological and psychological effects, but amongst them are a deleterious influence on behavior, memory loss, diminution of will-power, mood changes, paranoia, hallucinations, raised heart rate and blood pressure, as well as a strong link to psychosis, especially schizophrenia, primarily amongst younger users.
There is its alleged gateway effect to other “harder” drugs, while no one quite knows how long it resides in the body, where it accumulates in the fatty (lipid) tissue of the brain. And the stuff nowadays is significantly more potent than what was available a half-century ago, and is increasingly so. The “munchies” are the least of our worries."